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Dried Blood Spot Bioanalysis: Addressing the Sensitivity Challenge

Dried blood spots (DBS) have been used for many years in neonatal testing using either a heel or finger prick onto a piece of paper which is then dried and shipped for analysis. This approach has now been applied to the field of bioanalysis in preclinical, toxicokinetic, and clinical studies. DBS has several benefits.

Friday, September 3, 2010

Dried Blood Spot Bioanalysis: Addressing the Sensitivity Challenge

Tracking a chemical reaction using molecular interference

A new technique for following chemical reactions in real time makes a virtue of necessity, by using the radiation from non-reacting molecules as part of the detection method. As reported in Nature, this implementation of “high-harmonic interferometry” can be used to monitor both molecular structure and electron dynamics, the latter with attosecond time resolution.

Read more: Tracking a chemical reaction using molecular interference

 

Association of British Spectroscopists (ABS) Trust Fund Bursaries 2010

The ABS Trust invites UK-based university students undertaking spectroscopy research or utilising spectroscopy as a major component of their research to apply for a bursary award to attend a recognised scientific meeting to present an oral or poster presentation or to visit a place of learning to advance their spectroscopy knowledge and understanding.

More details and an application form may be requested from John Chalmers at This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

XRF unveils Leonardo Da Vinci’s faces

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Louvre1-sHow did Leonardo Da Vinci manage to paint such perfect faces? XRF analysis has shown the composition and thickness of each layer of material laid down by the painter. The results reveal that, in the case of glazes, thin layers of 1–2 µm have been applied.

Read more: XRF unveils Leonardo Da Vinci’s faces

   

NMR at new research centre makes important discovery in protein regulation

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The new Jean Jeener Bio-NMR Centre at the VIB Department of Molecular and Cellular Interactions, Vrije Universiteit Brussel, has already played a role in a scientific breakthrough that has been published Cell. Thanks to NMR, it is possible to determine the dynamic structure of proteins, and it was used to find out how the activity of certain proteins involved in the stress physiology of bacteria is regulated.

Read more: NMR at new research centre makes important discovery in protein regulation

   

Award for young NIR scientists

Since 2004 the Büchi Young Scientists NIRAward has been given to young scientists who worked during their diploma or doctoral thesis in the field of near infrared spectroscopy and achieved outstanding results. In the past many excellent scientists from NIR research groups all over the world have received this award.

Read more: Award for young NIR scientists

   

Lens for XPS to receive award

APPELS, differentially pumped Ambient Pressure PhotoElectron Lens System for photoemission studies, is one of four inventions from the US Department of Energy’s Lawrence Berkeley National Laboratory which have been recognised with the R&D 100 award for 2010 from R&D Magazine, which recognises the 100 most significant proven technological advances of the year.

Read more: Lens for XPS to receive award

   

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