SCIEX has introduced Acoustic Ejection Mass Spectrometry (AEMS) technology. AEMS incorporates the Open Port Interface (OPI) and Acoustic Droplet Ejection (ADE) and is being introduced by SCIEX ahead of commercialisation. SCIEX intends to bring the technology to market as Echo MS. In early testing, AEMS technology has shown the potential to reduce screening times from 115 days to 4 days for 1 million compounds. AEMS technology can also enable: Up to 50× faster sample analysis; accelerated speed of analysis, capable of up to three samples per second; low CVs of quantification (5–8 %), leading to high reproducibility regardless of the matrix; and sample analysis direct from the plate—no LC required, eliminating carry over and errors.
AEMS technology has been conceived by the Open Innovation Project, a collaboration between SCIEX and the US Department of Energy’s Oak Ridge National Laboratory. Led by SCIEX Principal Research Scientist, Tom Covey, the Open Innovation Project developed the OPI, a key part of AEMS technology.